Yujing Yin, Dengqiu Xu, Yan Mao, Liwei Xiao, Zongchao Sun, Jing Liu, Danxia Zhou, Zhisheng Xu, Lin Liu, Tingting Fu, Chenyun Ding, Qiqi Guo, Wanping Sun, Zheng Zhou, Likun Yang, Yuhuan Jia, Xinyi Chen, Z. Gan
{"title":"FNIP1 regulates adipocyte browning and systemic glucose homeostasis in mice by shaping intracellular calcium dynamics","authors":"Yujing Yin, Dengqiu Xu, Yan Mao, Liwei Xiao, Zongchao Sun, Jing Liu, Danxia Zhou, Zhisheng Xu, Lin Liu, Tingting Fu, Chenyun Ding, Qiqi Guo, Wanping Sun, Zheng Zhou, Likun Yang, Yuhuan Jia, Xinyi Chen, Z. Gan","doi":"10.1084/jem.20212491","DOIUrl":null,"url":null,"abstract":"Metabolically beneficial beige adipocytes offer tremendous potential to treat obesity and metabolic diseases. Yin et al. show that FNIP1 acts as a negative regulator of beige adipocyte thermogenesis to control systemic glucose homeostasis through modulating the ER Ca2+-ATPase SERCA.","PeriodicalId":23015,"journal":{"name":"The Tokushima journal of experimental medicine","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2022-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"6","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Tokushima journal of experimental medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1084/jem.20212491","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 6
Abstract
Metabolically beneficial beige adipocytes offer tremendous potential to treat obesity and metabolic diseases. Yin et al. show that FNIP1 acts as a negative regulator of beige adipocyte thermogenesis to control systemic glucose homeostasis through modulating the ER Ca2+-ATPase SERCA.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
