Epitope-based Multi-variant SARS-Cov-2 Vaccine Design: Shared Epitopes Among the Natural SARS-Cov-2 Spike Glycoprotein and 5 of its Variants (D614G, α, β, γ, δ) with High in Silico Binding Affinity to Human Leukocyte Antigen (HLA) Class II Molecules

Spyros A. Charonis, A. Georgopoulos
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引用次数: 1

Abstract

Page 9 of 14 Epitope-based Multi-variant SARS-Cov-2 Vaccine Design: Shared Epitopes Among the Natural SARS-Cov-2 Spike Glycoprotein and 5 of its Variants (D614G, α, β, γ, δ) with High in Silico Binding Affinity to Human Leukocyte Antigen (HLA) Class II Molecules Spyros A. Charonis1,2, Apostolos P. Georgopoulos1,2* 1The HLA SARS-CoV-2 Research Group, Brain Sciences Center, Department of Veterans Affairs Health Care System, Minneapolis, MN 55417, USA 2Department of Neuroscience, University of Minnesota Medical School, Minneapolis, MN 55455, USA
基于表位的多变体SARS-Cov-2疫苗设计:与人白细胞抗原(HLA)ⅱ类分子高硅结合亲和力的天然SARS-Cov-2刺突糖蛋白及其5种变体(D614G、α、β、γ、δ)共享表位
基于表位的SARS-Cov-2多变体疫苗设计天然SARS-Cov-2长链糖蛋白及其变体(D614G、α、β、γ、δ)与人类白细胞抗原(HLA)ⅱ类分子高硅基结合亲和力的共同表位Spyros A. charonis1,2, Apostolos P. Georgopoulos1,2* 1 HLA - cov -2研究组,退伍军人事务部卫生保健系统脑科学中心,明尼阿波利斯,MN 55417,美国2明尼苏达大学医学院神经学系,明尼阿波利斯,MN 55455,美国
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