Microbiote intestinal et obésité : impact des lipides bioactifs issus du système endocannabinoïde

IF 1.8 Q2 AGRONOMY
Patrice D Cani
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引用次数: 0

Abstract

De nombreux travaux ont associe le microbiote intestinal au developpement de desordres metaboliques. Parmi les mecanismes potentiellement impliques dans le dialogue bacteries-hotes, le systeme endocannabinoide (eCB) et ses lipides bioactifs jouent un role important. Nos travaux suggerent l’existence d’un dialogue a double-sens entre l’organisme et les bacteries : le tissu adipeux controlerait la fonction barriere de l’intestin; et les bacteries de l’intestin seraient capables de controler le metabolisme du tissu adipeux.
肠道微生物群与肥胖:内源性大麻素系统生物活性脂类的影响
许多研究将肠道微生物群与代谢紊乱的发展联系起来。在可能参与宿主-细菌对话的机制中,内源性大麻素系统(eCB)及其生物活性脂类发挥着重要作用。我们的研究表明,身体和细菌之间存在双向对话:脂肪组织控制着肠道的屏障功能;肠道细菌可以控制脂肪组织的代谢。
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来源期刊
CiteScore
4.70
自引率
14.30%
发文量
33
审稿时长
10 weeks
期刊介绍: OCL-Oilseeds and fats, Crops and Lipids is a peer-reviewed full Open-Access scientific journal devoted to fats, lipids and oil- and protein-crops. OCL covers the entire sector. The research papers and reviews published address a range of topical matters in agronomy, plant biology, biochemistry, analytical chemistry, lipid chemistry, as well as transversal research themes such as nutrition, the health-quality-food safety nexus, innovation and industrial processes, the environment and sustainable development, economics and social development. A particular feature of OCL is the inclusion of special thematic sections focusing on a topical subject among the Journal''s core domains. Invited contributors to these thematic sections are chosen with care in order to ensure the expression of a genuine cross-section of interests and expertise.
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