Application of metronomic chemotherapy in the treatment of advanced non-small cell lung cancer

Abstract

Metronomic chemotherapy is a brand-new and multi-target chemotherapy strategy. Totally different from the traditional chemotherapy, metronomic chemotherapy can exert synergistic and durable anti-tumor effects via multiple mechanisms, including cytotoxic effect, anti-angiogenesis, immune regulation and so on. Single and combined therapy modes of metronomic oral vinorelbine have good curative effects and safeties for the treatment of advanced non-small cell lung cancer. With the in-depth understanding of metronomic chemotherapy, it will certainly become an important treatment mode for advanced non-small cell lung cancer. Key words: Carcinoma, non-small-cell lung; Chemoradiotherapy; Drug therapy, combination; Metronomic chemotherapy; Vinorelbine