The combined effect of zinc and honey to increase hemoglobin and albumin levels in white rats induced by low protein diet

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2022-12-01 DOI:10.11591/ijaas.v11.i4.pp296-305

Endang Sri Sunarsih, Yoga Adhi Dana, Charisha Mahda Kumala

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Abstract

Undernutrition is a type of malnutrition. Malnutrition can endanger human life, particularly that of children. Honey, which has a high nutritional value, is one of the components that can be utilized to alleviate malnutrition. Zinc tablets, in addition to honey, are thought to boost hemoglobin (Hb) and albumin levels. Zinc, as an antioxidant and catalyst for biochemical events, aids in organ healing, particularly by restoring the role of enzymes in the process of food metabolism in the body. This study was conducted as an experimental study with a pretest-posttest design and a control group. Thirty Wistar rats were randomly distributed into six groups of five rats. The average Hb and albumin levels in the group of rats differ significantly, both in the single treatment and the combination of normal rats and malnutrition control. The groups that were given zinc and honey once a day had the greatest rise in hemoglobin, which was 0.5 g/dl (3.10%). The groups who received zinc and honey twice a day had the greatest rise in albumin (1.99 g/dl) (163.11%).

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锌和蜂蜜对低蛋白饮食诱导的大鼠血红蛋白和白蛋白水平升高的联合作用

营养不良是营养不良的一种。营养不良会危及人的生命，特别是儿童的生命。蜂蜜具有很高的营养价值，是可以用来缓解营养不良的成分之一。锌片，除了蜂蜜，被认为可以提高血红蛋白(Hb)和白蛋白水平。锌作为一种抗氧化剂和生化反应的催化剂，有助于器官愈合，特别是通过恢复体内食物代谢过程中酶的作用。本研究采用前测后测设计和对照组进行实验研究。30只Wistar大鼠随机分为6组，每组5只。在单独治疗和正常大鼠与营养不良对照组的联合治疗中，各组大鼠的平均Hb和白蛋白水平均有显著差异。每天给予一次锌和蜂蜜的组血红蛋白升高幅度最大，为0.5 g/dl(3.10%)。每天服用两次锌和蜂蜜的组白蛋白增加最多(1.99 g/dl)(163.11%)。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.