The Daily Expression Profile of Neuropeptides ( gnih, gnrh3, kiss1 and kiss2 ):A Study of Possible Interaction in the Brain of Zebrafish ( Danio rerio )

Journal of Endocrinology and Reproduction Pub Date : 2017-05-30 DOI:10.18519/JER/2016/V20/149827

Z. A. Khan, R. K. Labala, G. Mondal, Haobijam Sanjita Devi, Chongtham Rajiv, Thangal Yumnamcha, S. D. Devi, R. Bharali, S. Thorat, A. Chattoraj

{"title":"The Daily Expression Profile of Neuropeptides ( gnih, gnrh3, kiss1 and kiss2 ):A Study of Possible Interaction in the Brain of Zebrafish ( Danio rerio )","authors":"Z. A. Khan, R. K. Labala, G. Mondal, Haobijam Sanjita Devi, Chongtham Rajiv, Thangal Yumnamcha, S. D. Devi, R. Bharali, S. Thorat, A. Chattoraj","doi":"10.18519/JER/2016/V20/149827","DOIUrl":null,"url":null,"abstract":"Involvement of neuropeptides in the reproduction of fish (seasonal/regular) is known. The daily rhythmicity and their possible interaction of four major neuropeptides namely gnih , gonadotropin-inhibitory hormone; gnrh, gonadotropinreleasing hormone; kiss1/2, kisspeptin 1/2; is not known to any fish. Our present study on the whole brain of zebrafish (Danio rerio) aimed at the daily rhythmicity of the mRNA expression of these four neuropeptides in a 12 h light/12 h dark photoperiod (LD). Only kiss2 in its expression gives a rhythmicity but other three peptides are not rhythmic. Moreover, the expression of gnih is 10-fold lower than gnrh3. Our STRING network analysis suggests kiss2 act as the mediator to communicate with gnih , gnrh3, and kiss1. Our present finding is indicating the important role of kiss2 in mediating the reproductive signal and may play a central role in the synchronization of the environmental signal and reproductive periodicity.","PeriodicalId":15664,"journal":{"name":"Journal of Endocrinology and Reproduction","volume":"59 1","pages":"46-54"},"PeriodicalIF":0.0000,"publicationDate":"2017-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Endocrinology and Reproduction","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18519/JER/2016/V20/149827","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 1

Abstract

Involvement of neuropeptides in the reproduction of fish (seasonal/regular) is known. The daily rhythmicity and their possible interaction of four major neuropeptides namely gnih , gonadotropin-inhibitory hormone; gnrh, gonadotropinreleasing hormone; kiss1/2, kisspeptin 1/2; is not known to any fish. Our present study on the whole brain of zebrafish (Danio rerio) aimed at the daily rhythmicity of the mRNA expression of these four neuropeptides in a 12 h light/12 h dark photoperiod (LD). Only kiss2 in its expression gives a rhythmicity but other three peptides are not rhythmic. Moreover, the expression of gnih is 10-fold lower than gnrh3. Our STRING network analysis suggests kiss2 act as the mediator to communicate with gnih , gnrh3, and kiss1. Our present finding is indicating the important role of kiss2 in mediating the reproductive signal and may play a central role in the synchronization of the environmental signal and reproductive periodicity.

查看原文本刊更多论文

神经肽(gnih, gnrh3, kiss1和kiss2)的日常表达谱:斑马鱼大脑中可能相互作用的研究

神经肽参与鱼类的繁殖(季节性/规律性)是已知的。四种主要神经肽(gnih、促性腺激素抑制激素)的日常节律性及其可能的相互作用;促性腺激素释放激素;Kiss1/2, kisspeptin /2;是任何鱼都不知道的。我们对斑马鱼全脑(Danio rerio)的研究旨在研究这四种神经肽在12小时光照/12小时黑暗光周期(LD)下mRNA表达的日常节律性。只有kiss2在表达上具有节奏性，其他三个肽则没有节奏性。此外，gnih的表达量比gnrh3低10倍。我们的STRING网络分析表明，kiss2充当与gnih、gnrh3和kiss1通信的中介。我们目前的发现表明，kiss2在调节生殖信号中起着重要作用，并可能在环境信号和生殖周期的同步中发挥核心作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of Endocrinology and Reproduction

自引率

0.00%

发文量