HIGH-VOLUME AND HIGH-INTENSITY FUNCTIONAL TRAINING IN PATIENTS WITH MULTIPLE SCLEROSIS: A PILOT STUDY ON FEASIBILITY AND FUNCTIONAL CAPACITY

Tom C. A. Derikx, I. Brands, Arne T. Goedhart, Wouter H. Hoens, M. Heijenbrok-Kal, R. van den Berg-Emons
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引用次数: 1

Abstract

Objective To evaluate the feasibility of a high-volume and high-intensity functional training programme in patients with multiple sclerosis (MS), and to explore whether functional capacity improves. A further objective was to explore changes in muscle strength and aerobic capacity. Methods This pilot study comprised a 12-week intervention, with an 8-week follow-up period. The intervention consisted of 3 weekly 3-h training sessions, comprising functional resistance-, endurance-, and skills training. Feasibility (questionnaire), functional capacity (Timed Up and Go Test, 10-Meter Walk Test, and 6-Minute Walk Test), aerobic capacity (cardiopulmonary exercise test) and muscle strength (1 repetition maximum (RM) leg press) were evaluated. Results Seven patients completed the study. Patients attended a mean of 93% of the training sessions. One adverse event was reported, which was not related to the training programme. Patients scored positive or very positive on 86% of the feasibility aspects and scored an overall grade of 8.9 on a scale of 1–10 regarding satisfaction with the training programme. Functional capacity, aerobic capacity, and muscle strength seemed to be improved after the training programme, but the improvements were not always sustained. Conclusion This new high-volume and high-intensity functional training programme appeared to be feasible in patients with MS, and may improve their functional capacity, aerobic capacity and muscle strength. A large-scale controlled trial over a longer period of time is required to evaluate the added value of the training programme. LAY ABSTRACT Multiple Sclerosis (MS) is an autoimmune disorder which affects 2.3 million people worldwide. People with MS often have impaired physical fitness, which may induce fatigue. In this pilot study we evaluated a new and high-intensive training program. Patients trained for 12 weeks, three days a week, three hours a day. We explored whether the training program is feasible in MS, and whether patients improve their physical fitness. Seven patients completed the study, and attended on average 93% of the training sessions. Patients scored an overall grade of 8.9 on a scale of 1 to 10 regarding satisfaction with the training program. Physical fitness seemed to be improved, but improvements did not always preserve eight weeks after the training program. We concluded that the training program appears to be feasible in patients with MS, and may improve their physical fitness. However, a large controlled study is necessary to confirm these findings.
多发性硬化症患者的大容量和高强度功能训练:可行性和功能能力的初步研究
目的评价大容量、高强度的功能训练方案在多发性硬化症(MS)患者中的可行性,并探讨其功能能力是否得到改善。进一步的目标是探索肌肉力量和有氧能力的变化。方法本初步研究包括12周的干预和8周的随访。干预包括每周3次3小时的训练,包括功能性阻力、耐力和技能训练。评估可行性(问卷调查)、功能能力(计时起来和走测试、10米步行测试和6分钟步行测试)、有氧能力(心肺运动测试)和肌肉力量(1次最大重复(RM)腿推)。结果7例患者完成了研究。患者平均参加了93%的培训课程。报告了一个与培训方案无关的不良事件。患者在86%的可行性方面得分为肯定或非常肯定,并且在1-10的范围内对培训计划的满意度得分为8.9分。功能能力、有氧能力和肌肉力量似乎在训练计划后得到了改善,但这种改善并不总是持续的。结论这种新的大容量、高强度的功能训练方案在多发性硬化症患者中是可行的,可以提高患者的功能能力、有氧能力和肌力。需要在较长时间内进行大规模对照试验,以评价培训方案的附加价值。多发性硬化症(MS)是一种影响全球230万人的自身免疫性疾病。患有多发性硬化症的人通常身体机能受损,这可能会导致疲劳。在这项初步研究中,我们评估了一项新的高强度培训计划。病人接受了12周的训练,每周三天,每天三小时。我们探讨了训练方案在MS中是否可行,以及患者是否能提高他们的身体素质。7名患者完成了这项研究,平均参加了93%的训练课程。在1到10的评分范围内,患者对培训计划的满意度得分为8.9分。身体健康似乎得到了改善,但这种改善并不总是在训练计划结束后的八周内保持不变。我们的结论是,训练计划似乎是可行的MS患者,并可能提高他们的身体素质。然而,需要一项大规模的对照研究来证实这些发现。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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