Determination of the full structure and absolute stereochemistry of the antifungal agent FR-900848: an X-ray crystallographic study of (1R,3S,4R,6S,7S,9R,10S,12R)-quatercyclopropyl-1,12-dimethanediyl di-4-bromobenzoate

Abstract

Degradation studies and partial synthesis are used to establish the full structure and absolute stereochemistry of the nucleoside antifungal agent FR-900848.