Microcantilever based biosensor with electrical read-out method

Abstract

Recently, an all polymer system based biosensor with integrated optical read-out has been developed. Optical detection techniques are perhaps the most common due to their prevalent use in biology and life sciences. Fluorescence-based detection in Bio-MEMS has been applied to detection of cells within micro-chips, using antibody-based assays. Majority of the detection schemes in microarray and numerous lab-on-a-chip devices and applications utilize optical detection schemes. For size shrinkage, and to reduce the hardware we proposed the new read-out method which utilize the electrical detection method. The paper present design and analysis of microcantilever based biosensor based with electrical read-out method. This method is ideal for the manufacture of low cost disease diagnostic Kits. The sensor structure is designed and simulated using Coventorware software. The corresponding deflection with respect to voltage and stress is analyzed. To solve the fabrication process related issue of the sensor control circuit has been designed and tested using Spartan II-FPGA Kit & PCB. The reliability issues of the sensor are also studied.