The Prevalence of Dry Eye Syndrome in Rheumatoid Arthritis Patients in Saudi Arabia

Alaa Baghazal, S. Al-Mansouri, Rahaf Salem
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Abstract

STUDY AIM: The purpose of this study is to identify the prevalence of dry eye syndrome among Rheumatoid Arthritis patients in the Kingdom of Saudi Arabia. METHODS: This is a cross sectional study which includes 268 Rheumatoid Arthritis patients from Rheumatology Outpatient Clinic at King Khalid University Hospital in Riyadh, Kingdom of Saudi Arabia. Data collection was obtained through McMonnies questionnaire, which is used for dry eye syndrome screening. Data analysis included descriptive statistics computed for continuous variables, including means, standard deviation, minimum and maximum values, as well as 95% confidence interval (CI). RESULTS: Out of 268 Rheumatoid Arthritis patients, 79.9% were females and 20.1% were males, as Rheumatoid Arthritis is more common in females. Among females, a majority lied above the age of 45 with a percentage of 70.6%. Among our cohort, 59.3% (95% CI: 53.3–65) of Rheumatoid Arthritis patients had dry eye syndrome with 12.6% males and 87.4% females. The prevalence of dry eye syndrome was significantly associated with the duration of diagnosis of Rheumatoid Arthritis as 66.7% of patients who are diagnosed for more than 10 years had dry eye syndrome. CONCLUSION: In our cohort, 59.3% of patients had dry eye syndrome and 47.4% of them were aged above 45 years and 11.9% were between 25-45 years old. Females were more commonly affected with dry eye syndrome with a percentage of 87.4%. Therefore, screening for Dry Eye Syndrome in RA patients has a significant clinical value.
沙特阿拉伯类风湿关节炎患者干眼综合征患病率
研究目的:本研究的目的是确定沙特阿拉伯王国类风湿关节炎患者中干眼综合征的患病率。方法:这是一项横断面研究,包括268例来自沙特阿拉伯王国利雅得哈立德国王大学医院风湿病门诊的类风湿性关节炎患者。通过McMonnies问卷收集数据,用于干眼综合征筛查。数据分析包括对连续变量计算的描述性统计,包括平均值、标准差、最小值和最大值以及95%置信区间(CI)。结果:268例类风湿关节炎患者中,女性占79.9%,男性占20.1%,类风湿关节炎在女性中更为常见。在女性中,45岁以上占多数,占70.6%。在我们的队列中,59.3% (95% CI: 53.3-65)的类风湿关节炎患者有干眼综合征,其中男性12.6%,女性87.4%。干眼综合征的患病率与类风湿关节炎的诊断时间显著相关,诊断时间超过10年的患者中有66.7%患有干眼综合征。结论:在我们的队列中,干眼综合征患者占59.3%,其中47.4%的患者年龄在45岁以上,11.9%的患者年龄在25-45岁之间。干眼综合征以女性多见,占87.4%。因此,对RA患者进行干眼综合征筛查具有重要的临床价值。
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