Association of Neutrophil to Lymphocyte Ratio with In- hospital Outcome of Acute Heart Failure due to Acute Anterior ST-elevation Myocardial Infarction

Suchitra Basak, M. A. K. Akanda, M. Ullah, Sushanta Barua, M. Hasan, Md Shazedur Rahman, Mohammad Mamoon Islam, Md Gulam Mostafa
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Abstract

Background: Early detection and appropriate management play a key role in reducing the morbidity and mortality of acute heart failure in patients with acute myocardial infarction. Many prognostic factors have been assessed till date. This study aimed to evaluate the prognostic effect of NLR on in-hospital outcomes in patients with acute heart failure due to acute anterior ST elevation myocardial infarction. Methods: The present study was carried out in the Department of cardiology, Sir Salimullah Medical College & Mitford Hospital, Dhaka from January 2020 to December 2020. A total of 88 cases of acute heart failure due to acute anterior ST elevation Myocardial infarction patients are enrolled in this study. NLR was estimated and patients were divided into two groups based on the NLR (Group I NLR <6; Group II NLR ≥6). Then in-hospital outcome was observed and compared between two groups. Results: In-hospital mortality and length of hospital stay were higher among NLR ≥6 patients with statistical significance (11.6% vs. 40.9%, p<0.001). These patients also had high incidence of cardiogenic shock (25% vs. 43%, p>0.072), Arrhythmia (18% vs. 34%, p>0.089) but without statistically significant difference. Conclusion: In this study, we observed that in-hospital outcomes were worse in patients with acute heart failure due to acute anterior myocardial infarction with NLR ≥6. So NLR can be used as a predictor of outcome in acute heart failure patients. This association is independent of conventional cardiovascular risk factors. Cardiovasc j 2022; 15(1): 13-19
中性粒细胞与淋巴细胞比值与急性st段抬高型心肌梗死致急性心力衰竭的院内预后的关系
背景:早期发现和适当处理对降低急性心梗患者急性心衰的发病率和死亡率起着关键作用。迄今为止已经评估了许多预后因素。本研究旨在评估NLR对急性ST前抬高型心肌梗死致急性心力衰竭患者住院预后的影响。方法:本研究于2020年1月至2020年12月在达卡Sir Salimullah医学院和Mitford医院心内科进行。本研究共纳入88例急性ST前抬高型心肌梗死患者。估计NLR,根据NLR (I组NLR为0.072)、心律失常(18% vs. 34%, p>0.089)将患者分为两组,差异无统计学意义。结论:在本研究中,我们观察到NLR≥6的急性前路心肌梗死致急性心力衰竭患者的住院预后较差。因此NLR可以作为急性心力衰竭患者预后的预测指标。这种关联与传统的心血管危险因素无关。心血管病杂志[j] 2022;15 (1): 13 - 19
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