Teneligliptin – The Newest DPP4 Inhibitor

M. Kiran, H. Chandalia
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Abstract

Teneligliptin is the newest DPP4 inhibitor approved by the regulatory authority for the treatment of Diabetes mellitus. Teneligliptin scores over other 'gliptins' in being more economical and with better efficacy to control blood glucose and HbA1C levels. Teneligliptin additionally offers other pharmacological advantages like longer half-life, lesser IC50 value, tight and extensive binding to the DPP4 enzyme. Teneligliptin has been studies extensively for its safety and efficacy in various clinical trials conducted internationally. This review article comprehensively documents the available clinical and pharmacological data for Teneligliptin in the treatment of Diabetes mellitus.
Teneligliptin是fda批准用于糖尿病治疗的最新DPP4抑制剂。在控制血糖和糖化血红蛋白水平方面,替尼格列汀比其他“格列汀”更经济、更有效。此外,Teneligliptin还具有其他药理优势,如半衰期较长,IC50值较低,与DPP4酶紧密而广泛的结合。在国际上进行的各种临床试验中,对Teneligliptin的安全性和有效性进行了广泛的研究。本文综述了替尼格列汀治疗糖尿病的临床和药理学资料。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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