A Suggested Clinical Classification for the Equine Sarcoid

Derek C. Knottenbelt BVM&S, DVM&S, DipECEIM, MRCVS
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引用次数: 153

Abstract

The equine sarcoid, a fibroblastic tumor, is the most prevalent equine skin tumor and can affect all equidae. The sarcoid should be regarded as a tumor of fibroblasts. Involvement of the epidermis is a feature of most types but is not an obligatory feature. There are six visually recognizable types that correlate closely with the histology. The occult (superficial) type features alopecia, scaling, and skin thickening. The verrucose type has a prominent warty or verrucous appearance. There are two subtypes of the nodular form. Type A nodules are usually isolated individual or lobulated congregations of spherical subcutaneous masses. Type B nodules have cutaneous involvement that precludes independent movement of the overlying skin. Fibroblastic sarcoids have a fleshy fibrovascular appearance, often closely resembling granulation tissue. Type 1 fibroblastic sarcoids are pedunculated, whereas type 2 have a broad locally invasive base. The malignant sarcoid is an aggressive locally invasive form that extends widely into adjacent skin and subcutis. Mixed forms are common, and it is probably true that the large majority of sarcoid lesions have mixed components of two or more types.

马肉瘤的临床分类建议
马肉瘤是一种纤维母细胞肿瘤,是最常见的马皮肤肿瘤,可影响所有马科动物。肉瘤应视为成纤维细胞肿瘤。表皮受累是大多数类型的特征,但不是必需的特征。有六种视觉上可识别的类型,与组织学密切相关。隐蔽性(浅表性)型以脱发、脱屑和皮肤增厚为特征。疣状型具有突出的疣状或疣状外观。结节状有两种亚型。A型结节通常是孤立的单个或分叶状的球形皮下肿块。B型结节累及皮肤,妨碍其上覆皮肤的独立运动。纤维母细胞肉瘤具有肉质纤维血管外观,通常与肉芽组织非常相似。1型纤维母细胞肉瘤有带梗,而2型有广泛的局部浸润基底。恶性肉瘤是一种侵袭性的局部浸润形式,可广泛扩展到邻近皮肤和皮下。混合形式是常见的,这可能是真的,绝大多数肉瘤病变有两种或两种以上类型的混合成分。
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