Pregnancy Rate in Women with Normal Uterine Cavity and those with Corrected Uterine Cavitary Lesions in ICSI Cycles

Abstract

Aim: To investigate the pregnancy rate in women with normal uterine cavity and those with previously corrected uterine cavitary lesions, assessed by hysteroscopy in ICSI cycles. Study Design: A prospective cohort study . Materials and Methods: The study included women undergoing ICSI cycles. Patients were allocated into two groups, patients with normal uterine cavity (group 1, n=122) and patients with previously corrected uterine cavitary lesions (group 2, n=122). Office hysteroscopy was performed post-menstrual. The main outcome measure was clinical pregnancy rate. Secondary outcomes were the implantation rate and the take home baby rate. Results: In both groups the mean±SD of the total amount of gonadotrophins used, duration of stimulation, peak estradiol level, endometrial thickness and number of mature follicles, the implantation rate there was not statistically significant different in both groups (2.22 ± 0.84 vs. 2.46 ± 0.95, p =0.419). Also, the pregnancy rate showed no statistically significant difference between both groups (33.6% vs. 23.8%, p =0.089). Conclusion: Correction of uterine cavitary lesions makes the implantation rate and pregnancy rate to be comparable to women with normal uterine cavity.