Stefanos Chatzidakis, D. Lamnisos, V. Constantinides, A. Kyriacou, A. Economides, P. Economides
{"title":"Impact of autoimmune thyroiditis on primary hyperparathyroidism","authors":"Stefanos Chatzidakis, D. Lamnisos, V. Constantinides, A. Kyriacou, A. Economides, P. Economides","doi":"10.20883/medical.e737","DOIUrl":null,"url":null,"abstract":"Aim. Primary hyperparathyroidism (PHPT) often coexists with thyroid diseases. Current guidelines advise preoperative ultrasound (US) examination of the thyroid gland for thyroid nodular disease or concomitant malignancy but not evaluation for autoimmune thyroiditis (AIT). The impact of autoimmune thyroiditis on the clinical presentation and intraoperative course of PHPT is not clear.\nMaterial and methods. We retrospectively assessed the medical records of 21 patients with PHPT who underwent parathyroidectomy. Clinical, biochemical, ultrasonographic and intraoperative data were evaluated.\nResults. There was a longer duration of parathyroidectomy in patients with AIT than in those without (113.3 min vs. 93.9 min, P=0.03). A lower rate of kidney stones was noted in patients with autoimmune thyroiditis (44.4% vs. 0%, P=0.03). Patients with AIT were more symptomatic, but this was not significant. There was no difference between the two groups in the prevalence of osteoporosis or thyroid nodular disease.\nConclusions. A significantly longer duration of parathyroidectomy was seen in PHPT patients with AIT. Patients with PHPT undergoing surgery should be investigated for autoimmune thyroiditis, as this may affect surgical planning.","PeriodicalId":16350,"journal":{"name":"Journal of Medical Science","volume":"29 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Medical Science","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.20883/medical.e737","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Aim. Primary hyperparathyroidism (PHPT) often coexists with thyroid diseases. Current guidelines advise preoperative ultrasound (US) examination of the thyroid gland for thyroid nodular disease or concomitant malignancy but not evaluation for autoimmune thyroiditis (AIT). The impact of autoimmune thyroiditis on the clinical presentation and intraoperative course of PHPT is not clear.
Material and methods. We retrospectively assessed the medical records of 21 patients with PHPT who underwent parathyroidectomy. Clinical, biochemical, ultrasonographic and intraoperative data were evaluated.
Results. There was a longer duration of parathyroidectomy in patients with AIT than in those without (113.3 min vs. 93.9 min, P=0.03). A lower rate of kidney stones was noted in patients with autoimmune thyroiditis (44.4% vs. 0%, P=0.03). Patients with AIT were more symptomatic, but this was not significant. There was no difference between the two groups in the prevalence of osteoporosis or thyroid nodular disease.
Conclusions. A significantly longer duration of parathyroidectomy was seen in PHPT patients with AIT. Patients with PHPT undergoing surgery should be investigated for autoimmune thyroiditis, as this may affect surgical planning.
的目标。原发性甲状旁腺功能亢进(PHPT)常与甲状腺疾病共存。目前的指南建议术前超声(US)检查甲状腺甲状腺结节疾病或伴随的恶性肿瘤,但不评估自身免疫性甲状腺炎(AIT)。自身免疫性甲状腺炎对PHPT临床表现和术中病程的影响尚不清楚。材料和方法。我们回顾性评估了21例接受甲状旁腺切除术的PHPT患者的医疗记录。对临床、生化、超声及术中资料进行评价。AIT患者的甲状旁腺切除术时间较无AIT患者长(113.3 min vs. 93.9 min, P=0.03)。自身免疫性甲状腺炎患者肾结石发生率较低(44.4%比0%,P=0.03)。AIT患者的症状更明显,但这并不显著。两组在骨质疏松症和甲状腺结节疾病的患病率方面没有差异。PHPT合并AIT患者的甲状旁腺切除术持续时间明显延长。接受手术的PHPT患者应检查自身免疫性甲状腺炎,因为这可能影响手术计划。