Aberrancy in CNS Signals and other Factors Related to Altered Homeostasis, Obesity and Metabolic Syndrome

Abstract

‘The Obese-Obese World’: The obesity and metabolic syndrome (MetS) are a global epidemic of such magnitude that the today’s health scenario can be also influence sympathetic outflow to BAT. Conclusion - Fallouts of Neurosignal Aberrancy: The obese subjects with BMI > 30 show atrophy in the frontal lobes, anterior cingulate gyrus, hippocampus, and thalamus. MetS affects various cognitive domains including executive functioning, processing speed, and overall intellectual functioning. There is impaired vascular reactivity, endothelial dysfunction, neuro-inflammation, oxidative stress and altered brain metabolism.