Clinical profile of endometrial histopathological patterns in Abnormal Uterine Bleeding

S. Chauhan, K. Radhakrishnan
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引用次数: 2

Abstract

Aims: To study the association of clinical profile of patients with Abnormal Uterine Bleeding with the different endometrial histopathological patterns Methods: A retrospective cross-sectional study was done in the department of Obstetrics and Gynaecology at a hospital in Karnataka, India from January 2017 to January 2019. Medical records were reviewed for all the cases of abnormal uterine bleeding who underwent endometrial biopsy. Results: There were 148 records of endometrial biopsies; >55% were in 41-50 years age group; 28% had postmenopausal bleeding; and 28% presented with menorrhagia. Menorrhagia and menometrorrhagia were equally common under 50 years of age. The various physiological patterns of endometrium (proliferative, secretory & menstruating endometrium) were noted in more than half the cases (51%). Proliferative endometrium was in 37%, followed by hyperplasia without atypia in 22% and only 3% showed malignancy; all of whom were in the postmenopausal group. Even in women with post menopausal bleeding, proliferative pattern was the commonest (33%), followed by atrophic endometrium and malignancy. Atypical hyperplasia was found to be most commonly associated with post menopausal bleeding. Conclusions: Both physiological and non physiological endometrial patterns were seen almost equally among the AUB cases. The knowledge of endometrial pattern in a case of AUB helps to decide a plan of management. Endometrial sampling plays a very important role in management of AUB, especially in the age group of more than 40 yrs; i.e, the peri and post-menopausal age groups, where incidence of malignant or pre malignant conditions was noted to be the highest.
异常子宫出血的子宫内膜组织病理学模式的临床特征
目的:研究子宫异常出血患者的临床特征与不同子宫内膜组织病理学模式的关系方法:回顾性横断面研究2017年1月至2019年1月在印度卡纳塔克邦一家医院的妇产科进行。我们回顾了所有进行子宫内膜活检的异常子宫出血病例的医疗记录。结果:子宫内膜活检148例;55%的患者年龄在41-50岁之间;28%有绝经后出血;28%表现为月经过多。月经过多和月经过多在50岁以下同样常见。子宫内膜的各种生理模式(增殖、分泌和月经子宫内膜)在超过一半的病例(51%)中被注意到。增生性子宫内膜占37%,其次是增生无异型增生占22%,恶性肿瘤仅占3%;她们都是绝经后的一组。即使在绝经后出血的妇女中,增生模式是最常见的(33%),其次是萎缩子宫内膜和恶性肿瘤。不典型增生被发现与绝经后出血最常见。结论:在AUB病例中,生理性和非生理性子宫内膜形态几乎相同。了解AUB病例的子宫内膜模式有助于确定治疗计划。子宫内膜取样在AUB的治疗中起着非常重要的作用,特别是在40岁以上的年龄组中;即,围绝经期和绝经后年龄组,恶性或恶性前期情况的发生率最高。
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