Antibiotic Resistance Pattern Of Pseudomonas Aeruginosa Isolated From Clinical Specimens In A Tertiary Hospital In Northeastern Nigeria

Okon Ko, Agukwe Pc, Waliu Oladosu, Balogun St, A. Uba
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引用次数: 27

Abstract

A total of 106 greenish, pigmented consecutive non-duplicate Pseudomonas aeruginosa isolates from clinical specimens were examined. The mean age of the patients was 28.8+17.3 years, comprised of 56 (52.8%) males and 50 (47.2%) females. High prevalence of pseudomonal infections occurred more in age-group 20-29 years, 26 (24.6%) and least in 50-59years and >60years, 6 (5.7%), respectively. Majority of the isolates were recovered from wounds specimens, 42 (39%). Overall antibiotic susceptibility pattern showed that sparfloxacin demonstrated highest sensitivity of 84.9%, followed by ciprofloxacin, 69.8% and perfloxacin, 52.8%. Other results were cefuroxime, 49.1%, and ceftrazone, 13.2%. Majority of the isolates exhibited multidrug resistance pattern. In conclusion, the multidrug resistance pattern of P. aeruginosa isolates observed in this study posed a dire clinical consequence, especially in patients management with pseudomonal infections and infections control approach in hospital environment due to rapid dissemination of the strains
尼日利亚东北部某三级医院临床标本中铜绿假单胞菌的耐药性模式
从临床标本中分离出106株绿色、着色连续、不重复的铜绿假单胞菌。患者平均年龄28.8+17.3岁,其中男性56例(52.8%),女性50例(47.2%)。20 ~ 29岁假单胞菌感染率最高,为26例(24.6%),50 ~ 59岁和>60岁最低,为6例(5.7%)。大多数分离株来自伤口标本,42株(39%)。总体药敏图显示,司帕沙星敏感性最高,为84.9%,其次为环丙沙星69.8%,全氟沙星52.8%。其他结果为头孢呋辛,49.1%,头孢曲松,13.2%。大多数分离株呈现多重耐药模式。总之,本研究中观察到的铜绿假单胞菌多药耐药模式造成了可怕的临床后果,特别是在假单胞菌感染的患者管理和医院环境中感染控制方法中,由于菌株的快速传播
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