Correlation between Fertility Drug and the Likelihood of Gynecological Cancer - A Systematic Review.

Abstract

Background: There is increasing use of fertility drugs for ovulation induction and ovarian stimulation in assisted reproductive treatment like In Vitro Fertilization. For the treatment of subfertility, several medications are used to grow more eggs these drugs used to stimulate their ovaries may fuel cancer risk. In this review, recent literature regarding the correlation between fertility drug and cancer risk is reviewed to find out whether the medicines used to stimulate ovulation increase the risk of any gynecological cancer in women. Main body: Broad controversy exists in the literature about fertility treatment-induced cancer, although clinical trials are generally more focused. In order to present comprehensive strategies, the author has attempted to synthesize findings from Forty-seven research papers. The purpose of this study is to present a systematic review of the available evidence-based research paper concerning the relationship between fertility drug and gynecological cancers. Conclusion: The result of this study shows support for the correlation between fertility drugs and certain cancer risk, the correlation should continue to be monitored because the included studies had several limitations and multiple differences in the way they were conducted. However, we suggest the need to counsel women about their potential risk of Uterine/ Endometrial cancer and Breast Cancer in the future before any treatment procedure.