Morphogenesis of Neuroleptic Cardiomyopathy in Morphometric Light

Abstract

Aim: A comparative morphometric study of heart condition on the organ level of its organization in each clinical stage of neuroleptic cardiomyopathy. Methods and Results: In compliance with the modern requirements of evidential medicine the morphometric method of a research differing in objectivity and high informational content is used. For analysis of data from organometry of heart an own original method was used. It was found that on the organ level the process of cardiac remodeling ends during the latent stage of the disease. Progression of myocardial dysfunction is connected with the changes. Conclusion: During the morphogenesis of an antipsychotic cardiomyopathy a certain definition of the stage of clinical manifestations of a disease corresponding to the remodeling of the heart at the organ level is observed.