Peut-on prévenir la survenue de douleurs chroniques dans la polyarthrite rhumatoïde ?

Claire Daien , Jean Sibilia
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Abstract

Although the prognosis of rheumatoid arthritis (RA) has been revolutionised by the advent of targeted disease-modifying anti-rheumatic drugs, chronic pain persists in many RA patients. While some of this pain is related to failure of the current therapies to control inflammation, a large majority is non-inflammatory refractory pain. Understanding, managing and preventing this pain remains a major challenge. In this narrative review, we will first present the risk factors associated with their occurrence and the mechanisms involved. We will then discuss the prevention strategies that can be put in place today.

类风湿性关节炎慢性疼痛的发生可以预防吗?
虽然类风湿关节炎(RA)的预后已经随着靶向疾病改善抗风湿药物的出现而发生了革命性的变化,但许多RA患者仍然存在慢性疼痛。虽然其中一些疼痛与当前治疗方法控制炎症的失败有关,但绝大多数是非炎症性难治性疼痛。理解、管理和预防这种痛苦仍然是一项重大挑战。在这篇叙述性综述中,我们将首先介绍与其发生相关的危险因素及其机制。然后,我们将讨论今天可以实施的预防战略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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