Effect of Beta-blockers on Hypertension and Heart Failure with Reduced Ejection Fraction: A Systematic Review of Randomized Controlled Trials

Abstract

General objective The general objective of this study was to evaluate the effects of the different beta-blockers in patients with HTN and HFrEF. Specific objectives The specific objectives of this study were as follows: • To discuss the pathophysiologic mechanisms behind the development of HTN and HF • To determine which beta-blockers are effective in reducing rates of hospitalization, morbidity, and mortality among hypertensive patients with HFrEF.