Oral Health Influencing Systemic Health: A Journey of Crossroads

Abstract

It is rightly said that the mouth is the mirror of the body and no organ is disconnected to one and another. The various organ systems are interconnected to each other through the system biology through the flow of matter via blood vessels and lymph. The oral disease is mainly caused by periodontal microbiome mainly periodontal bacteria and viruses. The past literature suggests the link of oral and systemic diseases through focal infection and transient bacteremia contributing towards the inflammatory state in a number of systemic diseases, especially cardiovascular diseases and diabetes, have been strongly linked to oral health. Two mechanisms have been proposed to account for the connections that have been found. First and foremost, persistent oral inflammation can raise blood levels of inflammatory markers, which might impair immune function or add to the body's overall illness load. Second, systemic endotoxemia or bacteremia, which can affect diseases at distant sites or the entire body, might enter the bloodstream via the mouth cavity and act as a reservoir for harmful bacteria