P. Onishchenko, Yu. N. Zakharov, V. Borisov, K. Klyshnikov, E. Ovcharenko, Yu. Kudravceva, Y. Shokin
{"title":"Modeling of Hemodynamics in a Vascular Bioprosthesis","authors":"P. Onishchenko, Yu. N. Zakharov, V. Borisov, K. Klyshnikov, E. Ovcharenko, Yu. Kudravceva, Y. Shokin","doi":"10.17537/2021.16.15","DOIUrl":null,"url":null,"abstract":"\nThe study of blood flow in vascular bioprostheses is a rather complicated task, since the shape of the inner surface of the bioprosthesis is variable, due to xenogenic origin. Because of this, vortex zones can occur inside the vascular bioprosthesis. In addition, the flow structure may contain sections where the flow velocity is abnormally high. It is all the more difficult to assess the nature of the course when using this vascular bioprosthesis as a shunt. A numerical comparison of the blood flow in a bioprosthesis connected to the main vascular bed using the «end-to-end» and «end-to-side» methods (bypass) taking into account the heart rate and blood pressure was performed. It is shown that, due to the nonlinearity of the initial bioprosthesis geometry, the implantation method affects the blood flow. Because of this, vortex zones arise and, with certain combinations of parameters, the effects of «separation» of vortices.\n","PeriodicalId":53525,"journal":{"name":"Mathematical Biology and Bioinformatics","volume":"168 1","pages":"15-28"},"PeriodicalIF":0.0000,"publicationDate":"2021-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Mathematical Biology and Bioinformatics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.17537/2021.16.15","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Mathematics","Score":null,"Total":0}
引用次数: 1
Abstract
The study of blood flow in vascular bioprostheses is a rather complicated task, since the shape of the inner surface of the bioprosthesis is variable, due to xenogenic origin. Because of this, vortex zones can occur inside the vascular bioprosthesis. In addition, the flow structure may contain sections where the flow velocity is abnormally high. It is all the more difficult to assess the nature of the course when using this vascular bioprosthesis as a shunt. A numerical comparison of the blood flow in a bioprosthesis connected to the main vascular bed using the «end-to-end» and «end-to-side» methods (bypass) taking into account the heart rate and blood pressure was performed. It is shown that, due to the nonlinearity of the initial bioprosthesis geometry, the implantation method affects the blood flow. Because of this, vortex zones arise and, with certain combinations of parameters, the effects of «separation» of vortices.