Significance of Particulate Drug Delivery System in Anti-microbial Therapy

Abstract

Antimicrobial agents are the substances, used to kills or inhibit the growth of pathogenic microorganisms in living things. Several antimicrobial therapeutic agents have been exploited to treat infectious diseases caused by pathogenic microbes such as bacteria, fungi and viruses. These agents differ in their physicochemical, pharmacological properties and in their mechanisms of action. Typically, antimicrobials agents kill or inhibit the growth of bacteria by binding to some significant components of bacterial metabolism, and thereby alter the functional bimolecular synthesis or normal cellular activities. The successful antibacterial therapies necessitate presence of antibacterial agent at its target site and interfere with bacterial functions with an adequate effective concentration to achieve a desired result without producing the toxic effects [1].