The contribution of microembolic signals (MES) detection in cardioembolic stroke

Perspectives in Medicine Pub Date : 2012-09-01 DOI:10.1016/j.permed.2012.02.031

Martin A. Ritter

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引用次数: 3

Abstract

Background

Cardioembolic stroke accounts for about one third of all strokes. Microembolic signals (MES) are frequently found in patients with acute stroke. The role of MES in cardioembolic stroke is less well investigated.

Methods

Medline based literature review of clinical trials linking MES and stroke with cardiac sources of various risks.

Results

MES are a rare finding in patients with cardioembolic stroke as well as in sources of potential cardiac embolism (e.g. myocardial infarction, atrial fibrillation, left ventricular thrombus). The low number of patients with MES and the low number of MES during the investigation times leads to a limited statistical power of positive and negative findings. MES in patients with artificial heart valves and the DeBakey left ventricular assist device (LVAD) are predominantly gaseous and do not correlate with stroke risk. In patients with the Novacor LVAD, MES strongly correlate with stroke risk.

Conclusion

Currently, the role of MES in cardioembolic stroke is only limited due to both, the low prevalence of MES and the number of MES per investigation. Larger studies would be needed to strengthen this role.

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微栓塞信号(MES)检测在心源性卒中中的作用

心脏栓塞性中风约占所有中风的三分之一。急性脑卒中患者常出现微栓塞信号(MES)。MES在心脏栓塞性卒中中的作用研究较少。方法基于medline的文献综述将MES和卒中与各种心脏危险源联系起来的临床试验。结果在心源性卒中患者以及潜在心源性栓塞(如心肌梗死、心房颤动、左室血栓)中，sme是一种罕见的发现。MES患者数量少，调查期间MES数量少，导致阳性和阴性结果的统计效力有限。使用人工心脏瓣膜和DeBakey左心室辅助装置(LVAD)的患者的MES主要是气态的，与卒中风险无关。在使用Novacor LVAD的患者中，MES与卒中风险密切相关。目前，由于MES的低患病率和每次调查的MES数量，MES在心源性卒中中的作用受到限制。需要更大规模的研究来加强这一作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Perspectives in Medicine

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