Study on of Ethanol and Aqueous Extracts of Embelia ribes for Anthelmintic Properties

Asian Journal of Research in Medical and Pharmaceutical Sciences Pub Date : 2023-08-22 DOI:10.9734/ajrimps/2023/v12i4225

Pinkey Rawal, C. Ramesh, B. Sowmya, C. Ranjitha, L. Maria

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Abstract

Objectives: The present research study was conducted for the comparative evaluation of ethanol and aqueous extract of Embelia ribes for its in vitro anthelmintic properties. Methods: The authenticated leaves of plant Embelia ribes were dried and powdered. The powdered drug was defatted with petroleum ether and a part of marc leftover was subjected to ethanol extraction using Soxhlet apparatus. Another part was subjected aqueous extraction using chloroform water. The ethanol and aqueous extracts of Embelia ribes was subjected to preliminary phytochemical investigation. Both the extracts were evaluated for in vitro anthelmintic properties using earthworms. Results: The ethanol and aqueous extracts were revealed for the presence of alkaloids, glycosides, carbohydrates, flavonoids, tannins and phenols. The paralysis time and death time of worms were significantly reduced by the administration of ethanol and aqueous extracts of Embelia ribes. Conclusion: The result of the present investigation confirms the anthelmintic property of Embelia ribes.

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蛇腹草乙醇及水提物驱虫性能的研究

目的:本研究比较评价红腹蛇乙醇提取物和水提物的体外驱虫性能。方法:对植物气莲鉴定叶进行干燥、粉化处理。粉末状药物用石油醚脱脂，剩余部分用索氏装置乙醇提取。另一部分用氯仿水进行水萃取。对气莲乙醇提取物和水提取物进行了初步的植物化学研究。用蚯蚓对两种提取物进行体外驱虫药性能评价。结果:乙醇和水提液中均含有生物碱、苷类、碳水化合物、黄酮类、单宁类和酚类物质。乙醇和水提物均能显著缩短线虫的麻痹时间和死亡时间。结论:本研究结果证实了沙蚕的驱虫特性。

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Asian Journal of Research in Medical and Pharmaceutical Sciences

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