A clinical case of a combination of congenital toxoplasmosis associated with HIV and cytomegalovirus infections

Abstract

Toxoplasmosis is one of the problems of medicine, which has serious socio-economic significance. Congenital toxoplasmosis is manifested by severe fetal damage, its chronic course with lifelong preservation of the parasite in various organs and tissues, as well as the possibility of adverse perinatal outcomes. Purpose. To present a clinical case of congenital toxoplasmosis in a child: intrauterine chorioretinitis, meningoencephalitis in combination with HIV infection and current cytomegalovirus infection. Material and methods. A patient transferred from the Ust-Ilimsky maternity hospital to the city of Ivano-Matreninsky Children's Clinical Hospital in Irkutsk. Clinical data: in an HIV-infected mother, from 4 pregnancies, 4 births, a child was born at 39–40 weeks, 2930 gr. Results. Based on the conducted studies and examinations, the child was diagnosed with: Basic: Congenital toxoplasmosis: transferred intrauterine chorioretinitis, meningoencephalitis with the formation of calcifications of cerebral vessels, ventriculomegaly. Related: 1) HIV infection, stage 2 B, progression phase on ART, IC+2, moderate immunodeficiency; 2) Congenital cytomegalovirus infection; 3) UPU. Muscular DMZHP. Ltd. CH0; 4) Normochromic anemia of moderate severity. Conclusions. Congenital toxoplasmosis remains one of the serious problems and requires in-depth study. As a prevention of the development of congenital toxoplasmosis, it is necessary to diagnose infection with toxoplasmosis in women of fertile age during family planning. Keywords: congenital toxoplasmosis, chorioretinitis, meningoencephalitis, HIV infection, CMV infection