Factors influencing Adherence to Antiretroviral Therapy among People Living with HIV in an Urban and Rural Setting, Tanzania

The East and Central African Journal of Pharmaceutical Sciences Pub Date : 2019-03-27 DOI:10.4314/ECAJPS.V22I1

F. Mosha, Raphael Zozimus Sangeda, D. Ocheng, P. Risha, V. Muchunguzi, J. Vercauteren, E. Lyamuya, A. Vandamme, E. Kaale

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引用次数: 5

Abstract

Adherence is one of the most crucial determinants of treatment response to antiretroviral therapy (ART). An analytical cross-sectional study was conducted in 24 Care and Treatment Centres (CTC) in Dar es Salaam and Iringa regions in Tanzania. Data was collected using questionnaire and appointments records. A total of 943 patients attending at the care and treatment sites in Dar es Salaam and Iringa were recruited. Adherence based on keeping appointments and on four days recall was 65% and 70%, respectively. Adherence based on taking ART more than 95% of the time in one month was 83%. Satisfaction with health services, having treatment support, having knowledge on the use of ART, early presentation to CTC, and being on ART for more than one year, were associated with good adherence. Being in the urban region, using traditional medicine, medicine side effects and alcohol consumption problems negatively associated with adherence to ART. Keywords: Adherence barriers, antiretroviral therapy, HIV, Tanzania, rural, urban

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影响坦桑尼亚城乡艾滋病毒感染者坚持抗逆转录病毒治疗的因素

依从性是抗逆转录病毒治疗(ART)治疗反应的最关键决定因素之一。在坦桑尼亚达累斯萨拉姆和伊林加地区的24个护理和治疗中心进行了一项分析性横断面研究。通过问卷调查和预约记录收集数据。在达累斯萨拉姆和伊林加的护理和治疗地点共招募了943名患者。根据预约和四天回忆的依从性分别为65%和70%。一个月内接受抗逆转录病毒治疗的时间超过95%的依从性为83%。对卫生服务的满意度、获得治疗支持、了解抗逆转录病毒治疗的使用、早期向CTC就诊以及接受抗逆转录病毒治疗一年以上与良好的依从性相关。在城市地区，使用传统药物、药物副作用和酒精消费问题与坚持抗逆转录病毒治疗呈负相关。关键词:依从性障碍，抗逆转录病毒治疗，艾滋病毒，坦桑尼亚，农村，城市

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The East and Central African Journal of Pharmaceutical Sciences

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