The Effect of Pentazocine on Nausea and Vomiting Following Catheter Ablation

Abstract

: Pentazocine is an intravenously administered preoperative analgesic, but patients occasionally experience nausea and vomiting as an adverse reaction to this drug. As nausea and vomiting may interfere with the patient ʼ s postoperative rest, prevention of the reaction is necessary. This study aimed to survey postoperative nausea and vomiting （ PONV ） caused by pentazocine administered for catheter ablation. Patients receiving catheter ablation often experience pain during venipuncture and radiofrequency application, thus they are frequently placed under mild to deep sedation. Patients who underwent catheter ablation February and July 2016 were analyzed retrospectively. The preoperative analgesic dose and PONV were assessed. ％） 30 pentazocine, administration, subjects or thiopental 218 subjects ; mg mg group in the 30 mg group （ p ＝ 0.005 Analysis of postoperative 6 subjects in the 15 mg group （ 4.5 ％） and 14 subjects in the 30 mg group （ 11.5 ％） postoperative a higher percentage in the 30 mg group （ p ＝ 0.04 ） . Fur-thermore, the data indicate that being female is also an independent indicator of PONV. The results of this study suggest a relationship between pentazocine dose and PONV and that the incidence of PONV is directly related to an increased pentazocine dose.