Giant cerebellopontine Angle Tumor Surgery: Experience of a Tertiary Care Center in Lahore, Pakistan

T. Khokhar, Anam Fatima, S. Kiran, Muhammad Naveed Majeed, H. Abdul Majid, A. Bashir
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Abstract

Objectives:  In this case series, we report our experience of microsurgical resection of large and giant CPA tumors at the Department of Neurosurgery, Punjab Institute of Neurosciences (PINS). Materials and Methods:  This was a retrospective case series of 328 patients (mean age, 40 years) with large and giant CPA tumors (predominantly vestibular schwannomas) who underwent surgical removal using a retro sigmoid approach over 4 years. Results:  In the study, there were 58% (190) females while 42% (138) were males. 60% (197) of the tumors were right – sided and 40% (131) left – sided. Hearing loss was the main presenting complaint with 73% of the patients having non-serviceable hearing. There were 14 (4.3%) deaths reported during the retrospective analytic study. There were 3 cases of postoperative hemorrhage, and 11 patients expired due to post-operative wound infection. There were 13 cases diagnosed as having post-operative bacterial meningitis. Gross total tumor excision was achieved in 98% of patients based on postoperative imaging. There were 26 cases (8%) with postoperative CSF leakage that was managed with LP drain (5 patients) and in the rest VP shunt was done. Facial nerve function was graded according to the House Brackmann system. It was recorded in all patients following surgery: There were 16% patients with HB grade IV and 216 (66%) patients with HB grade III facial palsy.  Conclusion:  Suboccipital Retrosigmoid approach is ideal for dealing with giant CPA tumors. Complication rates in our series were comparable with other reported literature.
巨大的桥小脑角肿瘤手术:巴基斯坦拉合尔三级护理中心的经验
目的:在这个病例系列中,我们报告了我们在旁遮普神经科学研究所(PINS)神经外科显微手术切除大型和巨型CPA肿瘤的经验。材料和方法:这是一个回顾性的病例系列,328例患者(平均年龄40岁)患有大而巨大的CPA肿瘤(主要是前庭神经鞘瘤),他们在4年内采用乙状结肠复古入路手术切除。结果:女性190例,占58%,男性138例,占42%。60%(197例)肿瘤位于右侧,40%(131例)位于左侧。听力损失是主要的主诉,73%的患者听力不正常。回顾性分析研究中报告了14例(4.3%)死亡。术后出血3例,因术后伤口感染死亡11例。术后细菌性脑膜炎13例。根据术后影像,98%的患者实现了总体肿瘤切除。术后脑脊液漏26例(8%)采用LP引流术(5例),其余行VP分流术。根据House Brackmann系统对面部神经功能进行评分。在所有手术后患者中记录:有16%的HB IV级患者和216例(66%)HB III级面瘫患者。结论:枕下乙状窦后入路是治疗巨大CPA肿瘤的理想入路。本研究的并发症发生率与其他文献报道相当。
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