Results of surgery versus conservative follow up of adrenal incidentaloma

M. Kırnap, A. Akdur, E. Soy, Tevfik Avcı, G. Moray
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Abstract

Aim: The incidence of adrenal incidentaloma has increased recently due to increased magnetic resonance imaging (MRI), computed tomography scans (CT) and ultrasonography (USG). In our study, we aimed to demonstrate our radiologic, hormonal and clinical follow up of adrenal incidentaloma Material and methods: We retrospectively reviewed 276 patients with adrenal incidentaloma and excluded 73 of them. We collected the data of demographic findings, size, hormonal activity of the mass and malignancy. Results: Between 2007-2016 we diagnosed 203 adrenal incidentaloma patients in our clinic. The mean size of the tumors was 22,7±10,8mm. 157 (77,3%) of them were non-functional. We diagnosed 21 (10,3%) tumors with autonomous cortisol secretion, 9 (4,4%) cushing syndrome, 5 (2,5%) pheochromocytoma, 9 (4,4%) primary aldosteronism, 2 (1%) adrenocortical carcinoma. We suggested surgery to patients with 15 functional, 13 non-functional incidentaloma and 2 incidentaloma with suspicious malignancy. 21 cases preferred to undergo adrenalectomy and 12 of them had retroperitoneal laparoscopic adrenalectomy. During their routine follow up there was not any change in size of the tumors (p:0,12). Conclusion: The incidence of non-functional adrenal incidentolama (%77,3) was similar to the literature (4-5-6). There was not any change in size of the tumors during 3,9 year follow up of the patients. Although we had limited number of patients, we showed that radiologic evolvement contributes to differentiation of benign and malign lesions. By this way, we could follow patients more conservatively.
肾上腺偶发瘤的手术与保守随访的结果
目的:由于磁共振成像(MRI)、计算机断层扫描(CT)和超声检查(USG)的增加,肾上腺偶发瘤的发病率近年来有所增加。在我们的研究中,我们旨在展示我们对肾上腺偶发瘤的放射学、激素和临床随访。材料和方法:我们回顾性分析了276例肾上腺偶发瘤患者,并排除了其中的73例。我们收集了人口统计结果、肿块大小、激素活性和恶性程度的数据。结果:2007-2016年间,我们诊断了203例肾上腺偶发瘤患者。肿瘤平均大小为22.7±10.8 mm。其中无功能157例(77.3%)。我们诊断出21例(10.3%)伴有自主皮质醇分泌的肿瘤,9例(4.4%)库欣综合征,5例(2.5%)嗜铬细胞瘤,9例(4.4%)原发性醛固酮增多症,2例(1%)肾上腺皮质癌。我们建议对15例功能性偶发瘤,13例非功能性偶发瘤和2例可疑恶性偶发瘤进行手术治疗。21例首选行肾上腺切除术,其中12例行后腹腔镜肾上腺切除术。在他们的常规随访中,肿瘤的大小没有任何变化(p:0,12)。结论:非功能性肾上腺偶发瘤发生率(%77,3)与文献(4-5-6)相似。在对患者的3、9年随访中肿瘤的大小没有任何变化。虽然我们的病例数量有限,但我们发现放射学的发展有助于良恶性病变的区分。通过这种方式,我们可以更保守地跟踪病人。
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