Risk factors associated with mortality in patients with methanol poisoning: a retrospective study

Acta Medica Alanya Pub Date : 2022-11-22 DOI:10.30565/medalanya.1184894

H. Aydın, Fatih Doğanay, M. Erdoğan, H. Doğan, Attila Beştemir, Alpay Tuncar

{"title":"Risk factors associated with mortality in patients with methanol poisoning: a retrospective study","authors":"H. Aydın, Fatih Doğanay, M. Erdoğan, H. Doğan, Attila Beştemir, Alpay Tuncar","doi":"10.30565/medalanya.1184894","DOIUrl":null,"url":null,"abstract":"Aim: Methanol poisoning (MP) is an essential medical problem worldwide, and despite advances in diagnosis and treatment, the mortality rate in these cases is high. This study aimed to evaluate the clinical and laboratory factors to determine in-hospital mortality in patients with MP. \nMethods: This single-center, retrospective, observational study was conducted with adult 65 MP cases visiting the emergency department (ED) of a tertiary training and research hospital between January 01, 2017, and February 01, 2022. Data were statistically compared between survivors and non-survivors. \nResults: The in-hospital mortality rate was 41.5%. The rate of cases with respiratory distress, low Glasgow coma scale (GCS) (≤8), and delayed arrival to the hospital (>24 hours) was higher in the group of non-survivors compared to the group of survivors. Non-survivors had a higher anion gap (30.5 mEq/L vs. 25.5mEq/L), base excess (-25.0 mmol/L vs. -18.6 mmol/L), lactate (10.2 mmol/L vs. 2.2 mmol/L) levels, and lower pH (6.76 vs. 7.14) and bicarbonate (6.3 mmol/L vs. 10.3 mmol/L) levels than survivors (p","PeriodicalId":7003,"journal":{"name":"Acta Medica Alanya","volume":"1 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta Medica Alanya","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.30565/medalanya.1184894","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

Abstract

Aim: Methanol poisoning (MP) is an essential medical problem worldwide, and despite advances in diagnosis and treatment, the mortality rate in these cases is high. This study aimed to evaluate the clinical and laboratory factors to determine in-hospital mortality in patients with MP. Methods: This single-center, retrospective, observational study was conducted with adult 65 MP cases visiting the emergency department (ED) of a tertiary training and research hospital between January 01, 2017, and February 01, 2022. Data were statistically compared between survivors and non-survivors. Results: The in-hospital mortality rate was 41.5%. The rate of cases with respiratory distress, low Glasgow coma scale (GCS) (≤8), and delayed arrival to the hospital (>24 hours) was higher in the group of non-survivors compared to the group of survivors. Non-survivors had a higher anion gap (30.5 mEq/L vs. 25.5mEq/L), base excess (-25.0 mmol/L vs. -18.6 mmol/L), lactate (10.2 mmol/L vs. 2.2 mmol/L) levels, and lower pH (6.76 vs. 7.14) and bicarbonate (6.3 mmol/L vs. 10.3 mmol/L) levels than survivors (p

查看原文本刊更多论文

甲醇中毒患者死亡率相关的危险因素:一项回顾性研究

目的:甲醇中毒(MP)是世界范围内的一个重要医学问题，尽管在诊断和治疗方面取得了进展，但这些病例的死亡率很高。本研究旨在评估影响MP患者住院死亡率的临床和实验室因素。方法:这项单中心、回顾性、观察性研究纳入了2017年1月1日至2022年2月1日在一家三级培训和研究型医院急诊科(ED)就诊的65例成年MP病例。在幸存者和非幸存者之间进行数据统计比较。结果:住院死亡率为41.5%。呼吸窘迫、低格拉斯哥昏迷评分(GCS)(≤8)和延迟到达医院(>24小时)的病例率在非幸存者组高于幸存者组。与幸存者相比，非幸存者阴离子间隙(30.5 mEq/L vs. 25.5mEq/L)、碱过量(-25.0 mmol/L vs. -18.6 mmol/L)、乳酸(10.2 mmol/L vs. 2.2 mmol/L)水平更高，pH值(6.76 vs. 7.14)和碳酸氢盐(6.3 mmol/L vs. 10.3 mmol/L)水平更低

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Acta Medica Alanya

自引率

0.00%

发文量