Peripheral ameloblastoma: An etiology from surface epithelium? Case report and review of literature

Abstract

A 63-year-old African American male patient presented to the Dental Hygiene Clinic, LSU School of Dentistry for routine hygiene visit. On examination a 1.2 cm red, sessile nodule was noted on the lingual gingiva of the cuspid–bicuspid left mandibular region. The patient mentioned he had noticed it a few months ago and did not seek care as it was asymptomatic. The lesion was covered by normal mucosa, had a smooth surface, and a firm consistency. All the involved teeth tested vital. Radiographic examination of the area involved did not demonstrate any bony destruction. A biopsy was performed under local anesthesia and the microscopic examination revealed ameloblastic growth with an intact layer of covering non-keratinized squamous epithelium. The tumor islands consisted of a central mass of loosely connected stellate reticulum-like cells surrounded by a layer of columnar cells with well-polarized nuclei. The histological and clinical features were diagnostic for peripheral ameloblastoma. There have been a few well-documented cases of Peripheral ameloblastoma originating in non-tooth bearing regions of the jaw bones. This evidence supports an etiology from surface epithelium.