Screening of renal function among a group of physicians working in a hospital who are often self neglected

M. Kashem, A. Ullah, H. Imam, R. Biswas
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Abstract

Background: Prevalence of chronic kidney disease (CKD) has been increasing rapidly worldwide and early screening to detect kidney disease, particularly at its early stages is pivotal to stop its further deterioration. Population based study on detection at early stage of kidney disease and its prevalence are scanty in our country, especially among the medical professional personnel. Hence taking advantage of the observance of World Kidney Day 2020, we conducted a screening program for kidney disease organized at the Chattogram Maa O Shishu Hospital (CMOSH) premises among a group of physicians of the hospital. Methods: This was a cross sectional observational study among 67 physicians of different ranks (medical officer to professor), working at our hospital in different discipline. Age, body weight, height, Body Mass Index (BMI), blood pressure were documented, and urinary protein and serum creatinine were measured at a single sitting. Kidney function was estimated by calculating the glomerular filtration rate (GFR) using the Modification of Diet in Renal Disease (MDRD) formula. Kidney function was classified according to estimated GFR (eGFR) and Kidney Disease Outcomes Quality Initiative (K/DOQI) guidelines. Results: A total of 67 working physicians of the hospital were studied. Among them majority subjects (30) were in the age group of 20 to 29 years. Among all 11.9% participants had proteinuria (trace to 1 plus). The distribution of eGFR was symmetrical, with the majority (70.10%) of subjects in the 60 to 89 ml/min category, 11.90% had 30 to 59 ml/min category and only 17.90% of the study population had eGFR > 90 ml/min. An inverse relation between eGFR and age, and a direct relation between eGFR and BMI were observed. Conclusion: Proteinuria, low eGFR levels might be related with future decline in renal function among the studied subjects and so regular health checkup is important to abate the potential epidemic of kidney disease among the health professionals.
在医院工作的一群经常自我忽视的医生中进行肾功能筛查
背景:慢性肾脏疾病(CKD)的患病率在全球范围内迅速增加,早期筛查发现肾脏疾病,特别是在其早期阶段是阻止其进一步恶化的关键。我国以人群为基础的肾脏疾病早期检测及其患病率的研究还很缺乏,特别是在医疗专业人员中。因此,利用2020年世界肾脏日的纪念活动,我们在Chattogram Maa O Shishu医院(CMOSH)的一组医生中组织了肾脏疾病筛查项目。方法:采用横断面观察研究方法,对我院不同学科67名不同级别(医官至教授)医师进行调查。记录年龄、体重、身高、身体质量指数(BMI)、血压,单次测量尿蛋白和血清肌酐。采用肾脏疾病饮食修正(MDRD)公式计算肾小球滤过率(GFR)来评估肾功能。根据估计的GFR (eGFR)和肾脏疾病结局质量倡议(K/DOQI)指南对肾功能进行分类。结果:对该院67名在职医师进行调查。其中年龄在20 ~ 29岁的受试者占多数(30人)。11.9%的参与者有蛋白尿(可追溯至1 +)。eGFR呈对称分布,大多数(70.10%)受试者处于60 ~ 89 ml/min, 11.90%为30 ~ 59 ml/min,仅有17.90%的研究人群eGFR > 90 ml/min。eGFR与年龄呈负相关,与BMI呈正相关。结论:蛋白尿、低eGFR水平可能与未来肾功能下降有关,因此定期健康检查对减少肾脏疾病在卫生专业人员中的潜在流行具有重要意义。
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