{"title":"Unheard risk: considering the role of intrusive cognitions in relapse","authors":"A. Doonan, T. Buchanan","doi":"10.1080/16066359.2022.2140145","DOIUrl":null,"url":null,"abstract":"Abstract Substance use disorders (SUD) represent a pervasive and ongoing public health crisis responsible for many deaths and hospitalizations each year. Despite decades of research, we have yet to develop an effective cross-substance treatment model. Many who seek and enter treatment for SUD end up relapsing despite their intentions. Inconsistency in treatment success necessitates the identification of novel, universal therapeutic targets in the underlying core mechanisms of SUD. Determining the cognitive mechanisms which promote addictive behaviors is an essential first step to fully understand relapse and maintenance in SUD. The goal of the current review is to explore underlying cognitive processes which prolong SUD despite treatment. Through this, we propose a mechanistic model for how intrusive cognitions may jeopardize symptom improvement and SUD treatment success via risky decision making. Intrusive cognitions - images, words, memories, or impulses - demand little cognitive effort, and lend themselves to quick action and decisions. In the current paper, we present evidence which shows how intrusive cognitions, poorly inhibited, could impair the decision making process in SUD and lead to subsequent addictive behaviors.","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":null,"pages":null},"PeriodicalIF":16.4000,"publicationDate":"2023-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/16066359.2022.2140145","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
Abstract Substance use disorders (SUD) represent a pervasive and ongoing public health crisis responsible for many deaths and hospitalizations each year. Despite decades of research, we have yet to develop an effective cross-substance treatment model. Many who seek and enter treatment for SUD end up relapsing despite their intentions. Inconsistency in treatment success necessitates the identification of novel, universal therapeutic targets in the underlying core mechanisms of SUD. Determining the cognitive mechanisms which promote addictive behaviors is an essential first step to fully understand relapse and maintenance in SUD. The goal of the current review is to explore underlying cognitive processes which prolong SUD despite treatment. Through this, we propose a mechanistic model for how intrusive cognitions may jeopardize symptom improvement and SUD treatment success via risky decision making. Intrusive cognitions - images, words, memories, or impulses - demand little cognitive effort, and lend themselves to quick action and decisions. In the current paper, we present evidence which shows how intrusive cognitions, poorly inhibited, could impair the decision making process in SUD and lead to subsequent addictive behaviors.
期刊介绍:
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.