Functional Regeneration of Rats with Nerve Injuries via Transplantation of Bamboos

Nie Min, Meiling Zhang, Xiaohui Liu, Nie Shuai, Shi Wei, Yaosheng Yan, Suiping Han
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Abstract

Could plants grow in animals? Could the roots of a plant facilitate the regeneration of limb functions in animals with nerve injures? Does there exist rivalry and mutual immune between plants' and animals' immune system? So far there is no experiment or research report concerning these questions. In this paper, we show the experimental answers to these questions via transplantation of bamboos. We picked 36 rats weighing 250~280g randomly, and halved them into two groups: the control group (Group A) and the experiment group (Group B). The upper part of both the first lumbar (L1) and the second lumbar (L2) of all those rats were damaged, by transecting the dorsal nerve filament, about 5mm in length. We sutured and disinfected Group A. To Group B we transplanted the roots of bamboo in the nerve transection, with the roots clinging firmly to the two ends of the severed nerve, leaving the stems and leaves outside. During the 7 weeks after the surgery the research on behavioral comparison had been made. The rats in Group A were incontinent and paralyzed on their hindquarters. There was also no needling response on their hindquarters. When applying noxious hot water (48°C) to their hindquarters, no response was observed. The rats in Group B, however, recovered well---their limbs moved freely, responded quickly to prod, and shrank rapidly when noxious hot water touched their hindquarters. The situation of the bamboo that transplanted was good, the leaves were green and the stems were tall and straight. Therefore, the experimental result demonstrates that a plant could not only grow in an animal, but its roots can also facilitate the regeneration of limbs function. And there also exists a complex mechanism of immunity rivalry between the immune system of plants and that of animals, which results in the fast regeneration of nerve signal transmission path. We name the nerve regeneration induced by animals' immunity stimulated process Nerve Stimulated Regeneration (NSR). NSR approach might be a new way to reconstruct limbs function for people who are suffering from nerve injuries.
竹骨移植对神经损伤大鼠功能再生的影响
植物能在动物体内生长吗?植物的根能促进神经损伤动物肢体功能的再生吗?植物和动物的免疫系统之间是否存在竞争和相互免疫?到目前为止,还没有关于这些问题的实验或研究报告。本文通过竹的移植,给出了这些问题的实验答案。取体重250~280g的大鼠36只,随机分成对照组(A组)和实验组(B组)两组。所有大鼠第一腰椎(L1)和第二腰椎(L2)上部均被破坏,横断背神经丝,长度约5mm。对a组进行缝合和消毒,对B组在神经横断处移植竹根,根牢牢地附着在断神经的两端,茎叶留在外面。术后7周进行行为学比较研究。A组大鼠大小便失禁,后腿麻痹。它们的后躯也没有针刺反应。将48°C的有毒热水应用于它们的后躯时,没有观察到任何反应。然而,B组的老鼠恢复得很好——它们的四肢活动自如,对刺激反应迅速,当有毒的热水接触它们的后腿时,它们会迅速收缩。移栽的竹子情况良好,叶片青翠,茎长挺拔。因此,实验结果表明,植物不仅可以在动物体内生长,其根也可以促进肢体功能的再生。植物免疫系统与动物免疫系统之间存在着复杂的免疫竞争机制,导致神经信号传递路径的快速更新。我们将动物免疫刺激过程诱导的神经再生称为神经刺激再生(nerve stimulation regeneration, NSR)。NSR方法可能是神经损伤患者重建肢体功能的一种新方法。
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