Establishment and application of a high-quality comparative analysis strategy for the discovery and small-scale validation of low-abundance biomarker peptides in serum based on an optimized novel peptide extraction method

Tatsuya Saito, Y. Kawashima, Satoru Minamida, Kazumasa Matsumoto, Keita Araki, T. Matsui, M. Satoh, F. Nomura, M. Iwamura, T. Maeda, S. Baba, Y. Kodera
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引用次数: 10

Abstract

1 Laboratory of Biomolecular Dynamics, Department of Physics, Kitasato University School of Science 2 Center for Disease Proteomics, Kitasato University School of Science 3 Department of Urology, Kitasato University School of Medicine 4 Division of Natural Products Chemistry, Department of Medicinal Resources, Institute of Natural Medicine, University of Toyama 5 Clinical Proteomics Research Center, Chiba University Hospital 6 Department of Molecular Diagnosis (F8) Graduate School of Medicine, Chiba University
基于优化的新型多肽提取方法,建立高质量的血清低丰度生物标记肽发现和小规模验证对比分析策略并应用
1北里大学理学院物理系生物分子动力学实验室2北里大学理学院疾病蛋白质组学研究中心3北里大学医学院泌尿科4富山大学天然药物研究所天然产物化学部5千叶大学附属医院临床蛋白质组学研究中心6医学研究生院分子诊断部(F8),千叶大学
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