Nanostructured bioluminescence quenching sensor for detecting glucose.

Abstract

A new nanostructured biosensor by applying bioluminescent quenching technique is developed for detecting small molecules, e.g. glucose, at low concentration. It demonstrates the effect of glucose on the interaction between β-cyclodextrin (β-CD) conjugated luciferase and phenylboronic acid (PBA) conjugated gold nanoparticles (Au NPs).