Actinomycosis-Induced Lung Abscess and Empyema After the Treatment of Idiopathic Focal Segmental Glomerulosclerosis

Onur Derdiyok, D. Gürer, C. Ozturk, İ. Yalçınkaya
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Abstract

In adults, focal segmental glomerulosclerosis occurs in approximately 35% of nephrotic syndrome cases. Proteinuria can be reduced using steroids or immunosuppressive drugs in patients with focal segmental glomerulosclerosis (FSGS) with proteinuria at the nephrotic level. However, depending on the corticosteroid treatment, immunosuppression develops and opportunistic infections are predisposed. Actinomycosis, one of the opportunistic infections, is a rare bacterial lung infection. Clinically, it has seen most frequently in the cervicofacial region by 50-60%, then in the abdominal region by 25% and in the thoracic region by 15%. In our case of FSGS diagnosed with renal biopsy, after the steroid use, empyema and bronchopleural fistula (BPF) were developed. In this study, we report a case of successful management of actinomycosis and complications after tube thoracostomy and decortication with antibiotherapy treatment.
特发性局灶节段性肾小球硬化治疗后放线菌引起的肺脓肿和脓胸
在成人中,约35%的肾病综合征病例发生局灶性节段性肾小球硬化。局灶节段性肾小球硬化(FSGS)伴肾病水平蛋白尿的患者可使用类固醇或免疫抑制药物减少蛋白尿。然而,依赖于皮质类固醇治疗,免疫抑制发展和机会性感染易感。放线菌病是一种罕见的细菌性肺部感染,是机会性感染的一种。临床上,颈面最常见,占50-60%,其次是腹部,占25%,胸区占15%。在我们的病例中,通过肾活检诊断为FSGS,在使用类固醇后,出现了脓胸和支气管胸膜瘘(BPF)。在本研究中,我们报告一例成功的放线菌病和并发症后,管开胸和脱屑抗生素治疗。
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