COEXISTANCE OF DIABETES MELLITUS AND THYROID DISORDERS: A VIEW ON DYSFUNCTION OF THE ENDOCRINE SYSTEM

Asare Albert Adu, K. Daniel, Adedayo M. Adeyemi, O. Makharynska
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Abstract

Thyroid disorders in patients with diabetes mellitus were studied in 196 patients, divided into 4 main groups (hyperthyroidism in patients with diabetes, hypothyroidism in patients with diabetes, euthyroidism in patients with diabetes and diabetes patients without any thyroid pathology). It was found that diabetes and thyroid disorders have been shown mutually influence on each other and proved associations between both conditions. Compensation of thyroid function due to adequate therapy leads to controlled hyperglycemia, positive arterial hypertension disease mode and better diabetes mellitus outcome. Diabetes and thyroid disorders have been shown to mutually influence each other and associations between both conditions have long been reported. Compensation of thyroid function due to adequate therapy leads to controlled hyperglycemia, less frequency of DM and better DM outcome2.Hyperthyroidism as hypothyroidism impairs glycemic control in diabetic subjects, but hypothyroidism patients alter carbohydrate metabolism with inability to gain stable com-pensation of DM compering with euthyroidism and DM without thyroid dysfunction.3.Despite increased levels of BP, both systolic and diastolic, in patients with hypothyroidism group, prevalence of AH 3rdstage and AH complications were significantly higher in hyperthyroidism which requires more strict control of blood pressure levels and AH treatment in this group of patients.
糖尿病与甲状腺疾病共存:内分泌系统功能障碍的观点
对196例糖尿病患者的甲状腺功能障碍进行研究,将其分为4组(糖尿病患者甲状腺功能亢进、糖尿病患者甲状腺功能减退、糖尿病患者甲状腺功能亢进和无甲状腺病理的糖尿病患者)。研究发现,糖尿病和甲状腺疾病相互影响,并证实两者之间存在关联。适当的治疗使甲状腺功能得到补偿,导致高血糖得到控制,动脉高血压疾病模式呈阳性,糖尿病预后较好。糖尿病和甲状腺疾病已被证明是相互影响的,这两种疾病之间的关联早已被报道。适当的治疗使甲状腺功能得到补偿,可控制高血糖,减少糖尿病的发生频率,改善糖尿病的预后2。甲状腺功能亢进和甲状腺功能减退损害糖尿病患者的血糖控制,但与甲状腺功能亢进和无甲状腺功能障碍的糖尿病患者相比,甲状腺功能减退患者的碳水化合物代谢发生改变,无法获得稳定的糖尿病代偿。尽管在甲状腺功能减退患者中收缩压和舒张压水平均升高,但甲亢患者AH第三期和AH并发症的患病率明显更高,这需要更严格地控制血压水平和治疗AH。
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