Use of steroid therapy in immunoglobulin A-dominant poststaphylococcal glomerulonephritis

Abstract

Staphylococcal immunoglobulin A (IgA)-dominant infection-related glomerulonephritis (IgA-IRGN) is an emerging clinical entity seen in immunocompromised hosts. Antibiotics are the mainstay of treatment and the role of steroids is controversial. We present a review of literature and our recommendations on the use of steroids in the management of IgA-IRGN.

近年來，葡萄球菌感染相關的 IgA 型腎小球腎炎 (IgA-IRGN) 逐漸被世人認識，通常發生於免疫機能不全的病人，治療以抗生素療法為主，類固醇的角色則仍然存有爭議。以下我們將回顧 IgA-IRGN 的相關文獻，並對此病的臨床處置作出建議。