Enhanced Progression-Free Survival in a Phase 2 Trial of Personal Dendritic Cell Vaccines in Patients with Newly Diagnosed Glioblastoma

DE Piccioni, CM Duma, RV LaRocca, R. Aiken, TH Taylor, JA Carrillo, GI Nistor, HS Keirstead, Robert O. Dillman, DA Bota, Robert O. Dillman
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Abstract

Standard therapy of aggressive glioblastoma (GBM), which includes maximum safe surgical resection and concurrent radiation/temozolomide (RT/TMZ) followed by maintenance TMZ, is associated with poor progression-free survival (PFS) and overall
在新诊断的胶质母细胞瘤患者中,个人树突状细胞疫苗的2期试验提高了无进展生存期
侵袭性胶质母细胞瘤(GBM)的标准治疗,包括最大限度的安全手术切除和同时放疗/替莫唑胺(RT/TMZ),然后是维持TMZ,与较差的无进展生存(PFS)和总体相关
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