Role of Citicoline for Management of Myopic Amblyopia Patients in Teriary Care Hospital of India

Abstract

Introduction: Myopia is a very common condition affecting people worldwide. Current research aimed to study the effects of oral citicoline as treatment option in myopic amblyopia. Material and Methods: Patients of myopic amblyopia of age group 5-30 years were evaluated between June2018 to March2019. Detailed eye examinations including visual acuity, refraction, and dilated fundoscopy were done. Patients were randomly divided into 2 groups. 1 group of patients were given oral citicoline(500mg) daily for 12 weeks. Other group of patients was given placebo daily for 12 weeks. All patients were followed up to at monthly interval for 6 months; visual acuity and refraction were done in each follow up visit. Results: Total 378 patients with myopic amblyopia were identified. Visual acuity improved or became stable over time following citicoline therapy, as compared to placebo. Maximum improvement in visual acuity was from 6/60 to 6/9(p). Conclusion: Citicoline therapy resulted in significant improvement or stability of visual acuity in myopic amblyopic patients.