A Theoretical Approach for Detecting the Chikungunya Virus Based on 1D Photonic Crystals

Karuppiah Kathiresan, N. R. Ramanujam, Karuppiah Poovendran, S. Taya
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Abstract

In the current study, it is aimed at using defective 1D photonic crystals (PCs) to detect the chikungunya virus in various healthy and diseased blood samples composed of plasma, platelets, red blood cells, and uric acid. The proposed PC structure has 14 periods and consists of repeating SiC and SiO2 layers with a central cavity layer. When blood samples are injected into the cavity layer, the transmittance spectrum is examined theoretically by using a transfer matrix approach to determine how the wavelength of the defect mode changes. The cavity layer is 540 and 648 nm thick, and the work is carried out at different angles of incidence. The performance of the sensor is quantified by computing the sensitivity, figure of merit, quality factor, and limit of detection values of the sensor for various blood samples. The maximum sensitivity is 1205.5 nm RIU−1 and detection limit of the order is 10−6 in this proposed work. A lower value of sensor resolution of 0.01218 is also achieved. Such a high‐performance sensor is suitable for biosensing applications with better sensing capabilities.
基于一维光子晶体检测基孔肯雅病毒的理论方法
在目前的研究中,旨在利用缺陷1D光子晶体(PCs)检测由血浆、血小板、红细胞和尿酸组成的各种健康和患病血液样本中的基孔肯雅病毒。本文提出的PC结构有14期,由重复的SiC和SiO2层组成,中心有一个空腔层。当血液样本注入腔层时,理论上通过使用传递矩阵方法检查透射光谱,以确定缺陷模式的波长如何变化。空腔层厚度分别为540 nm和648 nm,工作在不同入射角下进行。通过计算传感器对各种血液样品的灵敏度、优值、质量因子和检出限来量化传感器的性能。该方法的最大灵敏度为1205.5 nm RIU−1,检测限为10−6阶。还实现了较低的传感器分辨率值0.01218。这种高性能传感器适用于具有更好传感能力的生物传感应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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