Circulating magnesium & Acute phage inflammatory reactant in North Indian adult population

International Journal of Biomedical and Advance Research Pub Date : 2018-05-01 DOI:10.7439/IJBAR.V9I4.4762

G. Shamnani, V. Gupta, Charushilla Rukadikar, Shraddha Singh, S. Tiwari, S. Bhartiy

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Abstract

Background: The increase of several serum proteins named acute phase reactants is a feature of the tissue response to inflammation . C-reactive protein (CRP) is one of the most sensitive acute-phase reactants in humans. Magnesium is found to be associated with these inflammatory reactants in previous studies. Objectives: The aim of this study was to investigate the relationship between serum magnesium levels and C- reactive protein in apparently healthy adults. Methods and material: This is a population based cross-sectional study. Total 130 adults of age between 25-65 years, were recruited with prior ethical approval and with written informed consent. Result: Mean value of serum magnesium was found to be 2.01mg/dl (±0.29) with range between 1.4mg/dl to 2.9mg/dl. Not a single case of severe hypomagnesemia (< 1.2 mg/dl) was found. Serum magnesium was found to have no significant correlation with C-reactive protein (r = -0.12, p=0.23). Conclusion: Authors report no significant co-relation between serum magnesium and CRP. Further larger studies are required to be done.

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北印度成年人群中循环镁与急性噬菌体炎症反应物

背景:几种被称为急性期反应物的血清蛋白的增加是组织对炎症反应的一个特征。c反应蛋白(CRP)是人体最敏感的急性期反应物之一。在之前的研究中，镁被发现与这些炎症反应物有关。目的:本研究旨在探讨表面健康成人血清镁水平与C-反应蛋白的关系。方法和材料:这是一项基于人群的横断面研究。共招募了130名年龄在25-65岁之间的成年人，并事先获得了伦理批准和书面知情同意。结果:血清镁的平均值为2.01mg/dl(±0.29)，范围为1.4 ~ 2.9mg/dl。未发现一例严重低镁血症(< 1.2 mg/dl)。血清镁与c反应蛋白无显著相关性(r = -0.12, p=0.23)。结论:血清镁与CRP无显著相关性。需要进行更大规模的研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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International Journal of Biomedical and Advance Research

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