REVIEW SENYAWA BIOAKTIF DAN KONSTITUEN KIMIA DARI TANAMAN COLEUS SEBAGAI KANDIDAT OBAT (REVIEW OF BIOACTIVE COMPOUNDS AND CHEMICAL CONSTITUENTS FROM COLEUS PLANTS AS DRUG CANDIDATES)

Indonesian Journal of Pure and Applied Chemistry Pub Date : 2023-08-31 DOI:10.26418/indonesian.v6i2.65149

Diana Natasya, Marsella Oktavioni, Yusnaidar Yusnaidar, I. L. Tarigan

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Abstract

Miana plants (Coleus) are plants with compound interest types. Miana leaves have various bioactive compounds and are widely used to treat various diseases such as fever, colds, coughs, headaches, asthma, constipation, and skin diseases. There are several types of miana plants, such as Coleus scutellarioides (L.) Benth., Coleus aromaticus Benth., Coleus atropurpureus (L.) Benth. and Coleus blumei benth. This review aims to review the content of bioactive compounds and chemical constituents of the plant and its potential as a drug candidate. The method applied to the review articles is in the form of literature studies from national and international journals. Based on the data used, the n-hexane extract of miana leaves found 11 chemical compounds. Then based on the phytochemical screening of miana plants, several bioactive compounds were produced such as sterols, terpenoids, alkaloids, phenols, flavonoids, amino acids, glycosides, lactones, catechols, and tannins. The function of the Coleus aromaticus plant is as an antioxidant, antiepileptic, antiurolytic, anticancer, antidiabetic, anthelmintic, antiviral, antiprotozoal activity, the inhibitory activity of microorganisms, against digestive diseases, respiratory disorders, and against cardiovascular disorders

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综述senyawa bioaktif Dan konstien kimia dari tanaman coleus sebagai candidate obat(花色植物候选药物的生物活性化合物和化学成分综述)

Miana植物(Coleus)是复利型植物。麻叶含有多种生物活性化合物，被广泛用于治疗各种疾病，如发烧、感冒、咳嗽、头痛、哮喘、便秘和皮肤病。miana植物有几种类型，如Coleus scutellarioides (L.)。Benth。，香堇底。，紫堇(L.)Benth。和蓝菖蒲底。本文综述了该植物的生物活性化合物和化学成分的含量及其作为候选药物的潜力。综述文章采用文献研究的方法，从国内和国际期刊。根据所使用的数据，迈阿密麻叶的正己烷提取物发现了11种化合物。通过对麻麻植物进行化学筛选，得到甾醇类、萜类、生物碱类、酚类、黄酮类、氨基酸类、苷类、内酯类、儿茶酚类、单宁类等多种生物活性化合物。芳香花的功能是抗氧化、抗癫痫、抗尿、抗癌、降糖、驱虫药、抗病毒、抗原虫活性、微生物抑制活性、抗消化系统疾病、呼吸系统疾病和心血管疾病

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Indonesian Journal of Pure and Applied Chemistry

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