Inotropic Requirement in Patients Undergoing Coronary Artery Bypass Grafting (CABG) in RSUP Dr. Hasan Sadikin Bandung in 2014-2016

Abstract

Inotropic agents are indicated to treat ventricular dysfunction that frequently found post-CABG surgery. However, the use of inotropic isn’t free from disadvantageous side effects and is related to higher morbidity and mortality in post-CABG surgery patients. Several risk factors are known to affect higher need for inotropic agents’ post-CABG surgery. This study aims to discover the inotropic requirement in patients undergoing CABG surgery based on age, sex, preoperative left ventricular ejection fraction (LVEF), comorbidities, cross clamping time (CCT), and cardiopulmonary bypass (CPB) duration in Hasan Sadikin General Hospital Bandung in 2014-2016. This study is a descriptive cross-sectional study done retrospectively through medical records. This study found the inotropic requirement post-CABG surgery was 130 patients (74.3%). The inotropic requirement based on age was 28 patients (80.0%) > 65 years old, 112 patients (75.7%) were male, 18 patients (66.7%) were female, 19 patients (100%) with  LVEF, 41 patients (85.4%) with DM, 20 patients (90.9%) with CKD, 44 patients (93.6%) with >90 minute CCT, 37 patients (90.2%) with >120 minute duration CPB. In conclusion, there was a higher inotropic requirement in patients with age > 65 years old, preoperative LVEF  comorbidities, CPB duration > 120 minutes and CCT > 90 minutes.