{"title":"Non-adaptive algorithms for threshold group testing with consecutive positives","authors":"","doi":"10.1093/imaiai/iaad009","DOIUrl":null,"url":null,"abstract":"\n Given up to $d$ positive items in a large population of $n$ items ($d \\ll n$), the goal of threshold group testing is to efficiently identify the positives via tests, where a test on a subset of items is positive if the subset contains at least $u$ positive items, negative if it contains up to $\\ell $ positive items and arbitrary (either positive or negative) otherwise. The parameter $g = u - \\ell - 1$ is called the gap. In non-adaptive strategies, all tests are fixed in advance and can be represented as a measurement matrix, in which each row and column represent a test and an item, respectively. In this paper, we consider non-adaptive threshold group testing with consecutive positives in which the items are linearly ordered and the positives are consecutive in that order. We show that by designing deterministic and strongly explicit measurement matrices, $\\lceil \\log _{2}{\\lceil \\frac {n}{d} \\rceil } \\rceil + 2d + 3$ (respectively, $\\lceil \\log _{2}{\\lceil \\frac {n}{d} \\rceil } \\rceil + 3d$) tests suffice to identify the positives in $O \\left ( \\log _{2}{\\frac {n}{d}} + d \\right )$ time when $g = 0$ (respectively, $g> 0$). The results significantly improve the state-of-the-art scheme that needs $15 \\lceil \\log _{2}{\\lceil \\frac {n}{d} \\rceil } \\rceil + 4d + 71$ tests to identify the positives in $O \\left ( \\frac {n}{d} \\log _{2}{\\frac {n}{d}} + ud^{2} \\right )$ time, and whose associated measurement matrices are random and (non-strongly) explicit.","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":null,"pages":null},"PeriodicalIF":16.4000,"publicationDate":"2023-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"100","ListUrlMain":"https://doi.org/10.1093/imaiai/iaad009","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 1
Abstract
Given up to $d$ positive items in a large population of $n$ items ($d \ll n$), the goal of threshold group testing is to efficiently identify the positives via tests, where a test on a subset of items is positive if the subset contains at least $u$ positive items, negative if it contains up to $\ell $ positive items and arbitrary (either positive or negative) otherwise. The parameter $g = u - \ell - 1$ is called the gap. In non-adaptive strategies, all tests are fixed in advance and can be represented as a measurement matrix, in which each row and column represent a test and an item, respectively. In this paper, we consider non-adaptive threshold group testing with consecutive positives in which the items are linearly ordered and the positives are consecutive in that order. We show that by designing deterministic and strongly explicit measurement matrices, $\lceil \log _{2}{\lceil \frac {n}{d} \rceil } \rceil + 2d + 3$ (respectively, $\lceil \log _{2}{\lceil \frac {n}{d} \rceil } \rceil + 3d$) tests suffice to identify the positives in $O \left ( \log _{2}{\frac {n}{d}} + d \right )$ time when $g = 0$ (respectively, $g> 0$). The results significantly improve the state-of-the-art scheme that needs $15 \lceil \log _{2}{\lceil \frac {n}{d} \rceil } \rceil + 4d + 71$ tests to identify the positives in $O \left ( \frac {n}{d} \log _{2}{\frac {n}{d}} + ud^{2} \right )$ time, and whose associated measurement matrices are random and (non-strongly) explicit.
期刊介绍:
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.