UV Spectrophotometric Determination of Allopurinol and Benzbromarone in their Binary Mixture using Artificial Neural Networks and Genetic Algorithm- Artificial Neural Networks

Abstract

Combination of ALP and BENZ has the advantages of greater therapeutic effect than with either drug alone. This combination causes manifold reduction in uric acid concentrations in plasma and urine as compared to double dose of the individual drug when used alone. Also, this combination helps to decrease the dose of each active ingredient, and as a result, decreases the side effects of each of component if given separately in high doses. (3)